NR-CL

Name: NR-CL
Brand: HumanPro
SKU: FI051

23111-00-4

NR-CL

NR-CL•Anti-aging

Structure: NR-CL structure

CAS: 23111-00-4

MF: C11H15ClN2O5

MW: 290.7

Synonyms

Nicotinamide riboside chlorideNicotinamide B-D Riboside Chloride(WX900111)Nicotinamide Riboside.ClNicotimide riboside chloridePyridinium, 3-(aminocarbonyl)-1-β-D-ribofuranosyl-, chloride (1:1)3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium chloride3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride

Usage

Nicotinamide Riboside Chloride (NR-CL) is primarily used as an efficient and safe NAD+ (Nicotinamide Adenine Dinucleotide) precursor to elevate intracellular NAD+ levels, thereby supporting cellular energy metabolism, mitochondrial health, and organismal anti-aging. Furthermore, it has obtained GRAS (Generally Recognized As Safe) status and can be directly used as a functional ingredient in dietary supplements and foods to provide vitamin B3 and confer additional health benefits.

Specification

99%+

Description

Overview

Nicotinamide Riboside Chloride, chemically named 3-Carbamoyl-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-pyridin-1-ium chloride, also known as 1-(β-D-Ribofuranosyl)nicotinamide chloride, is a crystalline, stable salt form of Nicotinamide Riboside (NR).

EINECS: 200-184-4

Product Categories: NMN;Food additive;API;1;23111-00-4

Characteristics

Appearance & Form: White solid

Biological Source: milk

Storage Temperature: under inert gas (nitrogen or Argon) at 2-8°C

Solubility: Soluble to 100 mM in DMSO and to 100 mM in water

Water Solubility: 10mg/mL, clear, colorless

Stability: Hygroscopic

Applications

Based on its core mechanism of elevating NAD+ and its GRAS safety profile, Nicotinamide Riboside Chloride is primarily applied in the following fields:

1. Dietary Supplements & Functional Foods (Core Application):

Healthy Aging & Anti-Aging: As a core ingredient in products designed to enhance cellular energy, support mitochondrial function, and activate sirtuin pathways for promoting healthy aging.

Metabolic Health: Used in supplement formulations aimed at supporting metabolic health, improving insulin sensitivity, and weight management.

Energy & Sports Performance: For developing products intended to boost physical energy, alleviate exercise fatigue, and promote recovery.

Neurological Health: As an ingredient in supplements supporting brain health, cognitive function, and neuroprotection.

2. Pharmaceutical R&D:

As a lead compound or active ingredient for investigating its potential in treating diseases associated with declining NAD+ levels, such as neurodegenerative disorders, metabolic syndrome, cardiovascular diseases, and certain myopathies.

3. Scientific Research:

As a standard tool molecule or interventional agent for studying NAD+ metabolism, mitochondrial biology, aging mechanisms, metabolic regulation, and neuroscience.